Best Tylenol Deals Today — Up to 50% Off on Amazon

Q: How often are Tylenol deals updated?

We refresh the Tylenol deals on this page three times daily. Prices and availability are pulled live from Amazon, so what you see is current.

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When a reader clicks through and buys, GoatGoatGoat may earn a small affiliate commission from Amazon at no extra cost to the reader. That commission funds the editorial work behind these pages.

The Best Tylenol Deals Today

12 active Tylenol deals

Tylenol has been the leading American acetaminophen brand since 1955 and remains the pain reliever in millions of medicine cabinets. The Extra Strength caplets, the 8-Hour Arthritis formula, and the Children's and Infants' lines are the perennials. Bulk multi-packs offer the best per-pill price. We refresh Tylenol deals three times daily. The biggest discounts typically appear during Prime Day, back-to-school season, and the cold-and-flu pre-winter window. A reliable brand to keep an eye on if you go through a bottle every few weeks and want to stop paying full retail at the drugstore.

-30%

Tylenol Extra Strength Pain Reliever & Fever Reducer, Round Coated Tablets, 500 mg Acetaminophen Pain Relief Pills for Headache, Toothache & Minor Arthritis Pain, 225 ct

$18.64 $26.59

Price Drop

Amazon

-28%

Tylenol Sinus Severe Daytime Caplets, Non-Drowsy, Pain Reliever, Pressure and Nasal Congestion Relief, Fever Reducer, Expectorant, Acetaminophen, Guaifenesin, Phenylephrine HCL, 24

$7.64 $10.67

Amazon

-28%

Tylenol Cold + Flu Severe Day & Night Caplets Combo Pack for Multi-Symptom Cold & Flu Symptom Relief, Cough, Sore Throat, and Headache Relief, Acetaminophen Pain Reliever, 24 ct

$7.69 $10.67

Amazon

-28%

Tylenol Cold + Flu Severe Medicine Caplets for Cold & Flu Symptom Relief, Fever Reducer, Pain Reliever, Cough Suppressant, Nasal Decongestant & Expectorant with Acetaminophen, 24 c

$7.67 $10.67

Amazon

-27%

Tylenol PM Extra Strength Nighttime Pain Reliever & Sleep Aid Caplets, 500 mg Acetaminophen & 25 mg Diphenhydramine HCl, Relief for Nighttime Aches & Pains, Non-Habit Forming, 150

$19.31 $26.59

Amazon

-25%

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Extra Strength Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes, 500 mg Acetaminophen, 24 ct

$4.97 $6.59

Amazon

-25%

Tylenol 8 Hour Acetaminophen 650 mg Extended Release Caplets, Fast Acting Bi-Layer Design, Quick & Long Lasting Pain Relief for Muscle, Joint, Back & Arthritis Aches, Fever Reducer

$12.47 $16.59

Amazon

-25%

Children’s Tylenol Liquid Oral Suspension Medicine, Acetaminophen Pain Reliever & Fever Reducer for Cold + Flu Symptoms & Sore Throat, Aspirin-, Ibuprofen- & Alcohol- Free, Grape,

$7.68 $10.28

Amazon

-25%

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Fast, Strong Pain Relief, Fever Reducer, 500 mg Gelcaps with Laser‑Drilled Holes for Fast Release, OTC Medicine, 100 Count

$12.47 $16.59

Amazon

-25%

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Fast, Strong Pain Relief, Fever Reducer Medicine, 500 mg Gelcaps with Laser‑Drilled Holes for Fast Release, Value Size, 225

$22.97 $30.59

Amazon

-23%

Tylenol 8 Hour Arthritis Pain Relief Extended-Release Tablets, 650 mg Acetaminophen, Joint Pain Reliever & Fever Reducer Medicine, Oral Pain Reliever for Arthritis & Joint Pain, 50

$8.25 $10.69

Amazon

-22%

Children’s Tylenol Chewables with 160 mg Acetaminophen, Pain Reliever & Fever Reducer for Kids’ Cold + Flu Symptoms, Headache, Sore Throat & Toothache, Aspirin-Free, Grape Flavor,

$7.98 $10.28

Amazon

About Tylenol Deals

How often are Tylenol deals updated?

We refresh the Tylenol deals you see here three times daily. Prices and availability are pulled live from Amazon, so what you see is current.

Are these the lowest Tylenol prices?

Each deal shown is at least 20% off the manufacturer's list price. Amazon adjusts prices throughout the day, so we recommend grabbing a deal you like rather than waiting on a lower number.

When does Tylenol typically go on sale?

The biggest Tylenol discounts on Amazon usually appear during Prime Day (July), the Big Spring Sale (March), and Black Friday/Cyber Monday week. Smaller sales run throughout the year, especially around major holidays.

How do you make money from these links?

When you click through and buy, we may earn a small affiliate commission from Amazon at no extra cost to you. That commission keeps the lights on so we can keep finding deals.

The Best Tylenol Deals Today

Tylenol Extra Strength Pain Reliever & Fever Reducer, Round Coated Tablets, 500 mg Acetaminophen Pain Relief Pills for Headache, Toothache & Minor Arthritis Pain, 225 ct

Tylenol Sinus Severe Daytime Caplets, Non-Drowsy, Pain Reliever, Pressure and Nasal Congestion Relief, Fever Reducer, Expectorant, Acetaminophen, Guaifenesin, Phenylephrine HCL, 24

Tylenol Cold + Flu Severe Day & Night Caplets Combo Pack for Multi-Symptom Cold & Flu Symptom Relief, Cough, Sore Throat, and Headache Relief, Acetaminophen Pain Reliever, 24 ct

Tylenol Cold + Flu Severe Medicine Caplets for Cold & Flu Symptom Relief, Fever Reducer, Pain Reliever, Cough Suppressant, Nasal Decongestant & Expectorant with Acetaminophen, 24 c

Tylenol PM Extra Strength Nighttime Pain Reliever & Sleep Aid Caplets, 500 mg Acetaminophen & 25 mg Diphenhydramine HCl, Relief for Nighttime Aches & Pains, Non-Habit Forming, 150

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Extra Strength Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes, 500 mg Acetaminophen, 24 ct

Tylenol 8 Hour Acetaminophen 650 mg Extended Release Caplets, Fast Acting Bi-Layer Design, Quick & Long Lasting Pain Relief for Muscle, Joint, Back & Arthritis Aches, Fever Reducer

Children’s Tylenol Liquid Oral Suspension Medicine, Acetaminophen Pain Reliever & Fever Reducer for Cold + Flu Symptoms & Sore Throat, Aspirin-, Ibuprofen- & Alcohol- Free, Grape,

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Fast, Strong Pain Relief, Fever Reducer, 500 mg Gelcaps with Laser‑Drilled Holes for Fast Release, OTC Medicine, 100 Count

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Fast, Strong Pain Relief, Fever Reducer Medicine, 500 mg Gelcaps with Laser‑Drilled Holes for Fast Release, Value Size, 225

Tylenol 8 Hour Arthritis Pain Relief Extended-Release Tablets, 650 mg Acetaminophen, Joint Pain Reliever & Fever Reducer Medicine, Oral Pain Reliever for Arthritis & Joint Pain, 50

Children’s Tylenol Chewables with 160 mg Acetaminophen, Pain Reliever & Fever Reducer for Kids’ Cold + Flu Symptoms, Headache, Sore Throat & Toothache, Aspirin-Free, Grape Flavor,

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